The comparison effect of dexmedetomidine and propofol during laparoscopic cholecystectomy

Phase 2

Recruiting

Conditions: laparoscopic cholecystectomy patients.
Calculus of bile duct with cholecystitis, unspecified, without obstruction
K80.40

Registration Number: IRCT20200225046610N1

Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 70

Inclusion Criteria

The patients between 20 to 60 age years old
The candidate patients for laparoscopic cholecystectomy

Exclusion Criteria

The patients have class II or III obesity
Chronic liver disease
Diabetes
Kidney disease
Endocrine problems
Romatoid disease
The cardiovascular disease patients which use a beta-blocker drug that affects sympathies response and hormonal secretion and finally
The person uses benzo diazepines are excluded from this study

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Heart rate. Timepoint: At the beginning and end of the study. Method of measurement: Anesthesia Monitoring system.;Mean atrial blood pressure (MAP). Timepoint: At the beginning and end of the study. Method of measurement: Anesthesia Monitoring system.;Duration of anesthesia. Timepoint: At the beginning and end of the study. Method of measurement: Extraction of patient anesthesia sheet.;Plasma level of blood sugar. Timepoint: At the beginning and end of the study. Method of measurement: Lab by specto-photometery method.;Level of stress hormone (epinephrine, nor-epinephrine, cortisol). Timepoint: At the beginning and end of the study. Method of measurement: Lab by ELISA method.

Secondary Outcome Measures

Name	Time	Method
Post operative nausea and vomiting (PONV). Timepoint: After release of recovery room each 6 Hr. Method of measurement: Sensation of nausea and vomiting by Visual Analogue Scale.