Natural History of Cherubism Observational Study

Completed

• Conditions: Cherubism
• Interventions: Other: no interventions

• Registration Number: NCT01916772
• Lead Sponsor: The Cleveland Clinic

Brief Summary

To observe the natural history of cherubism.

Detailed Description

The investigators will take a history and examine patients with cherubism to determine the natural history of the disease. The investigators also may take skin or blood samples (IRB approved 7256) from patients to learn more about this disorder.

Study Timeline

• Study Start: 2013-07
• Study First Submitted: 2013-07-25
• Study First Submitted QC: 2013-08-02
• Study First Posted: 2013-08-06
• Primary Completion: 2016-09
• Study Completion: 2016-09
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-06
• Last Update Posted: 2017-01-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 33

Inclusion Criteria

patients with cherubism

Exclusion Criteria

patients without cherubism

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
cherubism patients	no interventions	no interventions

Primary Outcome Measures

Name	Time	Method
Disease progression	10 years	We will take a history and examine patients with cherubism and look for disease progression.

Secondary Outcome Measures

Name	Time	Method
patient growth	10 years	We will measure height and weight
bone abnormalities	10 years	We will take panorex radiographs.

Trial Locations

Locations (1)

Cleveland Clinic; 🇺🇸 Cleveland, Ohio, United States