Effect of dairy-based high-protein, variable-carbohydrate diets and exercise on muscle maintenance and movement

Not Applicable

Completed

• Conditions: Obesity; Sarcopenia; Diet and Nutrition - Obesity

• Registration Number: ACTRN12612000021875
• Lead Sponsor: Professor John Hawley

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Body Mass Index (BMI) between 27-40 kg/m2 i.e. classified as overweight, class I Obese or class II Obese; Sedentary

Exclusion Criteria

Metabolic risk factors (hypercholesterolemia, hyperinsulinemia, and hyperglycemia, hypertenisive), heart and other organ disease, orthopaedic injury, gastrointestinal disease, clinically diagnosed dairy protein allergy, clinically diagnosed lactose intolerance.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in body composition: lean mass (kg) and fat mass (kg) as measured by Dual-energy X-ray absorptiometry (DXA) and anthropometric measures[Measured at baseline and at 8 and 16 weeks after intervention commencement]

Secondary Outcome Measures

Name	Time	Method
Strength and Cardio-respiratory fitness.<br>Strength will be assessed using four common resistance exercises (seated leg extension, hamstring curls, seated row and chest-press) through 1 repetition maximum (1RM) tests. Cardio-respiratory fitness will be measured through a VO2 max test where a facemask and heart rate monitor are worn throughout an increasing intensity test to fatigue.[Measured at baseline and at 8 and 16 weeks after intervention commencement];Blood profile (lipids; glucose and insulin (HOMA index)[Measured at baseline and at 8 and 16 weeks after intervention commencement];Daily energy expenditure will be measured using Sensewear armbands which measures motion, accelerometry, galvanic skin response, skin temperature and heat flux to give a measure of energy expenditure over several days[Measured at baseline and at 8 and 16 weeks after intervention commencement]