Adductor canal block with different additives for total knee replacement surgery

Not yet recruiting

Conditions: Unilateral primary osteoarthritisof knee,

Registration Number: CTRI/2020/10/028528

Lead Sponsor: AIIMS RISHIKESH

Brief Summary: Adductor canal block is a ultrasound guided regional anaesthesia technique, involves infiltration of local anaesthesia to the saphenous nerve,nerve to vastus medialis. Hypothesis: Adding two different analgesic drugs along with ropivacaine will show the efficacy of adjuvants in terms of prolong of duration and quality of analgesia in post- operative period

Aim: To study and compare dexmedetomidine and fentanyl with ropivacaine as analgesics post operatively given through single- shot block in Primary unilateral total knee replacement

Objectives: To compare duration of analgesia (request for first rescue analgesia) after single-shot adductor canal block with Numeric rating scale

Material &methods: A triple blinded randomised control trial

Sample size: 35 patients in each group

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 70

Inclusion Criteria

ASA â€“I, II Patients undergoing primary unilateral total knee replacement.

Exclusion Criteria

1.BMI > 35 kg/m2 2.Associated coagulation disorders 3.Infection at the site of injection 4.Severe cardiac,renal or hepatic dysfunction 5.Allergy to test drug 6.Any preâ€“ existing sensory or motor impairement 7.Patient with cognitive impairement 8.Patient refusal to participate 9.Emergency surgery.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare duration of analgesia (request for first rescue analgesia) after single-shot adductor canal block with ropivacaine and adjuvants (dexmedetomedine, fentanyl) in patients at rest undergoing primary unilateral total knee replacement with Numeric rating scale	At the first request for rescue analgesia in the post operative period during first 24 hours

Secondary Outcome Measures

Name	Time	Method
1.To assess pain scores by numerical rating scale (NRS) post operatively	2.To compare total rescue analgesia requirement in first 24hour after block

Trial Locations

Locations (1): AIIMS RISHIKESH
🇮🇳
Dehradun, UTTARANCHAL, India
AIIMS RISHIKESH
🇮🇳Dehradun, UTTARANCHAL, India
Dr Yashwant Singh Payal
Principal investigator
7906235754
dryspayal05@gmail.com