Empirical Comperative Study Of Variation Blood Level Antibody Vitamin D at Different Groups Of Patients Compared Healthy Peoples And The Correlation Between Vitamin D Level
试验速览
- 阶段
- 不适用
- 入组人数
- 64
- 主要终点
- Presence of Anti Vitamin D Antibodies in Blood Sample
研究概览
简要总结
The aim of this study is to detect antibodies to vitamin D in the serum at Different Groups of patients and healthy volunteer. A second goal is to find the relation between Vitamin D Antibody and Vitamin D level.
详细描述
Vitamin D and its metabolites have a significant role in the calcium homeostasis and bone metabolism. Vitamin D deficiency as measured by serum 25(OH)D below 20 ng/mL (50 nmol/L) may contribute to the development of osteoporosis and Osteomalacia.
Several studies have clearly demonstrated that low 25(OH)D levels are associated with more comorbidities, higher estimated cardiovascular risk and autoimmune diseases.
Exposure to the ultraviolet (UV) rays in sunlight is the major source of vitamin D. other sources are dairy products enriched with vitamin D.
Vitamin D deficiency can result from inadequate exposure to sunlight, malabsorption including inflammatory bowel disease, celiac disease and patients undergone resection of the small intestine and inadequate intake of dairy products enriched with vitamin D.
Another possible explanation for vitamin D deficiency is the presence of neutralizing autoantibodies to vitamin D.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients treated in Meir Medical Center
- •Data on serum vitamin D values
- •18 years old
- •Patient hereby declare that he\she agree to participate the clinical trial
排除标准
- •Patient refuses to sign Informed Consent.
- •Patients without vitamin D values
结局指标
主要结局
Presence of Anti Vitamin D Antibodies in Blood Sample
时间窗: 1 year
次要结局
未报告次要终点
研究者
yair levy
Head of Internal Medicine
Meir Medical Center