Evaluation of Non-invasive Hemoglobin Monitoring in Children With Congenital Heart Diseases
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Congenital Heart Disease
- Sponsor
- Cairo University
- Enrollment
- 56
- Locations
- 1
- Primary Endpoint
- non-invasive hemoglobin
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The investigators will evaluate the accuracy of non-invasive hemoglobin monitor (Sp-Hb) compared to traditional laboratory hemoglobin (Lab-Hb) in children with congenital heart disease. The investigators will also compare the accuracy of Sp-Hb in cyanotic children to acyanotic children.
Detailed Description
Blood hemoglobin is measured daily in clinical practice. Laboratory measurement (Lab-Hb) of is the gold standard for assessment of blood hemoglobin. Recently, non-invasive monitors had been introduced. Non-invasive measurement of hemoglobin (Sp-Hb) would save time and minimize the risk of infection. Blood sampling in children is usually more difficult and stressful; moreover, it also carries the risk of iatrogenic anemia. Radical-7 (Masimo corporation, Irvine, CA) is a device that operates using the principle of co-oximetry . Radical-7 had been validated in various clinical purposes. Measurement of blood hemoglobin is an important application for Radical-7 device. Non-invasive hemoglobin (Sp-Hb) measurement has been frequently validated in adults; as well as in pediatric patients; however, its accuracy in children with congenital heart disease was not investigated. Congenital heart disease infants usually undergo major operations and frequently need transfusion of blood. Moreover, these patients have special circulatory physiology that might impact the device accuracy. It had been recently reported that the performance of co-oximetry in congenital heart disease children is poor in measurement of oxygen saturation specially at oxygen saturation under 75%; however, its accuracy in measurement of hemoglobin was not investigated yet. In this study, the investigators will evaluate the accuracy of Sp-Hb compared to traditional Lab-Hb in children with congenital heart disease. the investigators will also compare the accuracy of Sp-Hb in cyanotic children to acyanotic children.
Investigators
Ahmed Hasanin
Assistant professor
Cairo University
Eligibility Criteria
Inclusion Criteria
- •infants and children less than 8 years
- •with congenital heart disease
Exclusion Criteria
- •refusal of the patient surrogate to share in the study
Outcomes
Primary Outcomes
non-invasive hemoglobin
Time Frame: 5 hours
the value of hemoglobin measured by radical-7 device in g/dL
Secondary Outcomes
- laboratory hemoglobin(5 hours)
- systolic blood pressure(5 hours)
- heart rate(5 hours)
- perfusion index(5 hours)
- plethysmography variability index(5 hours)
- diastolic blood pressure(5 hours)
- oxygen saturation from radical-7 device(5 hours)
- oxygen saturation from arterial blood gases(5 hours)