ACTRN12614001289606招募中未知
An investigation of the proportional change in plasma concentration of endogenous compounds relative to a pathway probe for CYP3A4 (midazolam) when administered with and without enzyme inducers and inhibitors, in healthy adult volunteers.
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 78
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Diagnosis
入排标准
- 年龄范围
- 21 Years 至 35 Years（—）
- 性别
- Male
入选标准
- •Non-smoker
- •BMI in the range 18 to 30
排除标准
- •1. Use of prescription, over-the-counter, complimentary or recreational drugs during seven days prior and for the duration of the study. Paracetamol is permitted.
- •2. Current cigarette smoker.
- •3. Consumption of grapefruit juice in the period 48 hours prior and for the duration of the study.
- •4. Prior allergy or adverse reaction to any of the drugs used in the study.
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