Outcome of Embryo Culture at Two Oxygen Tensions

Not Applicable

Completed

• Conditions: Embryo Development
• Interventions: Other: oxygen concentration in the culture atmosphere

• Registration Number: NCT00718822
• Lead Sponsor: University Medical Centre Maribor

Brief Summary

The purpose of this study is to assess whether reduced oxygen tension in embryo culture has any effect on clinical outcome.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-08
• Primary Completion: 2007-06
• Study Completion: 2007-09
• Status Verified: 2008-07
• Study First Submitted: 2008-07-17
• Study First Submitted QC: 2008-07-18
• Last Update Submitted: 2008-07-18
• Study First Posted: 2008-07-21
• Last Update Posted: 2008-07-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 647

Inclusion Criteria

• stimulated Intra Cytoplasmic Sperm Injection (ICSI) cycle

Exclusion Criteria

• less than one mature (metaphase II) oocyte at the time of denudation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
I	oxygen concentration in the culture atmosphere	5% oxygen concentration in the culture atmosphere
II	oxygen concentration in the culture atmosphere	20% oxygen concentration in the culture atmosphere

Primary Outcome Measures

Name	Time	Method
Ongoing pregnancy rate per cycle	10-11 weeks after embryo transfer

Secondary Outcome Measures

Name	Time	Method
clinical pregnancy rate, implantation rate, early pregnancy loss, fertilization rate, embryo quality

Trial Locations

Locations (1)

University Clinical Centre Maribor; 🇸🇮 Maribor, Slovenia