EUCTR2009-012643-42-NL进行中（未招募）不适用
Freezing of gait in Parkinson's disease: in search of the underlying mechanism and the application of a new treatment option - Freezing of gait in Parkinson's disease
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Parkinson's disease according to the criteria of the UK brain bank criteria.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- Presence of neurological central nervous system disorders other than idiopathic Parkinson's disease
- •- Surgical treatment for idiopathic Parkinson's disease, such as deep brain stimulation
- •- Dementia (i.e. a score below the cut-off of the Mattis Dementia Rating Scale)
- •- Other significant co-morbidity
- •- Contraindications to MRI scanning:
- •* metal objects in or near the body, such as a pacemaker, insuline pump, prothesis and/or metal splinters in eye.
- •* tattoos and/or piercings
- •* claustrophobia
- •- Controindications to the use of methylphenidate:
- •* cardiovascular disease, including moderate to severe hypertension
- •* structural cardiac abnormalities
- •* cardiomyopathy
- •* advanced arteriosclerosis
- •* hyperexcitability
- •* renal impairment
- •* porphyria
- •* bipolar disorder
- •* unstable personality
- •* anxiety disorder
- •* history of suicide attempts
- •* gilles de la tourette syndrome
- •* thyriod disease
- •* glaucoma
- •* pregnancy
- •* use of MAO-inhibitors
- •* use of vasopressors
研究者
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