The onset of walking and freezing in Parkinson patients compared to controls: A combined EEG-EMG study - Walking and freezing in PD

niversitair Medisch Centrum Groningen0 个研究点目标入组 85 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•Healthy individuals:
•o Perceived healthy
•o Age >= 18 years, age- and sex-matched with PD patients without FOG for case-control study
•o Right-handed according to the Annett Handedness scale
•o Written informed consent
•All PD Patients:
•o able to walk properly (Hoehn & Yahr scale: Stage 2-3)
•o PD diagnosis according to the UK Parkinson*s Disease Society Brain Bank criteria (A.J. Hughes, 1992)
•o Age < 70 (to limit the presence of vascular problems)
•o Right-handed according to the Annett Handedness scale
•o Written informed consent
•PD patients without FOG:
•o self-reported absence of FOG
•o Score=0 on (Dutch translation of) Giladi*s FOG questionnaire (Giladi et al., 2000)
•o Absence of FOG on clinical examination during rapid bidirectional 360* turns and dual tasking (Snijders et al., 2012)
•PD patients with FOG:
•o self-reported FOG
•o Score >=1 on (Dutch translation of) Giladi*s FOG questionnaire (Giladi et al., 2000) or presence of FOG on clinical examination during rapid bidirectional 360 degree turns and dual tasking (Snijders et al., 2012)

•All participants
•Mini Mental State Examination (MMSE) score <26 (to exclude low task performance due to cognitive disabilities)
•(other) neurological or motor disorder (for patients: other than PD)
•Use of medication influencing movement (for patients: other than for PD)
•PD patients
•Tremor-dominant PD

发起方