TCTR20230606004
Not yet recruiting
Phase 4
Effect of Cold Atmospheric Pressure Plasma on Orthognathic Surgery Wound Healing: A randomized controlled clinical trial
ConditionsHealthy male and female participants between 20 and 35 years old who are planning to take orthognathic surgeries using bilateral sagittal split ramus osteotomy technique with rigid osteofixation will be included in this study. Postoperative wound healing and microbial accumulation around the wound will be studied.Orthognathic surgery, wound healing, microbial colony counts, non-thermal atmospheric pressure plasma
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Healthy male and female participants between 20 and 35 years old who are planning to take orthognathic surgeries using bilateral sagittal split ramus osteotomy technique with rigid osteofixation will be included in this study. Postoperative wound healing and microbial accumulation around the wound will be studied.
- Sponsor
- Chulalongkorn University
- Enrollment
- 60
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Systematically healthy patient (ASA I)
- •2\. Adult (20\-35 years old) male or female
- •3\. Patient with norma gingival health (Gingival index 0\) preoperatively
- •4\. Patient planned for orthognathic surgeries with bilateral sagittal split ramus osteotomies
- •5\. Patient who agree to participate in research after explaining detail
Exclusion Criteria
- •1\.Smoking or chronic alcoholic patient
- •2\.Pregnant or lactating mother
- •3\.Patients with systemic diseases such as uncontrolled diabetes mellitus, HIV, cancer, thyroid disease, immunocompromised host including HIV
- •4\.Patients with hereditary healing disorders
- •5\.Patients with long\-term corticosteroids or immunosuppressive agents
- •6\.Patient with a history of chemotherapy or radiotherapy
- •7\.Patients with a previous history of oral surgery within 2 months
- •8\.Patient with a plan for additional surgeries at the same time such as genioplasty or Lefort I osteotomies
- •9\.Any errors such as bad split happened during their orthognathic surgery
- •10\.Operative time more than 4 hours (since the first incision until the last suturing)
Outcomes
Primary Outcomes
Not specified
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