NCT05869526已完成不适用
A Comparison of the Effects of Krill Oil and Fish Oil Supplementation on Muscle Function in Older Adults: a Randomised Controlled Pilot Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 61
- 试验地点
- 1
- 主要终点
- Change in knee extensor maximal isometric torque ( MVC)
研究概览
简要总结
The aim of the study is to compare the effects of Krill Oil and Fish Oil supplementation on muscle function in older adults. The secondary aim is to investigate the mechanisms underlying the beneficial effects previously observed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
盲法说明
Supplements will be identical in look and taste
入排标准
- 年龄范围
- 60 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Older adults (aged 60 years or older). BMI less than 30kg/m2
排除标准
- •Participants (diagnosed and being treated for a pre-existing medical condition (cancer, kidney disease, liver disease, diabetes mellitus and cardiovascular disease, uncontrolled hypertension, gait disturbances limiting the ability to perform assessments of muscle function, dementia, affecting muscles known to use drugs (e.g., steroids). History of allergy to fish or fish oil and regular consumption of more than1portion of oily fish per week or use of fish oil or krill oil supplements will also be excluded.
结局指标
主要结局
Change in knee extensor maximal isometric torque ( MVC)
时间窗: Change from baseline to 16 weeks
Knee extensor maximal isometric torque measured during a maximal voluntary contraction
次要结局
- Change in fat mass(Change from baseline to 16 weeks)
- Blood sample(Change from baseline to 16 weeks)
- Change in Muscle thickness(Change from baseline to 16 weeks)
- Neuromuscular Junction (NMJ)(Change from baseline to 16 weeks)
- Change in gait speed(Change from baseline to 16 weeks)
- Change in Grip strength(Change from baseline to 16 weeks)
- Force steadiness during submaximal isometric knee extensor contractions(Change from baseline to 16 weeks)
- Change in lean mass(Change from baseline to 16 weeks)
- Change in Chair rise time(Change from baseline to 16 weeks)
研究者
Stuart Gray
Professor
University of Glasgow
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Investigating the Effects of Krill Oil and Krill Protein on Post-exercise Muscle Protein MetabolismHypertrophyNCT05774444University of Glasgow48
已完成
不适用
Krill Oil and Muscle in Older AdultsAgingSarcopeniaNCT04048096University of Glasgow102
已完成
不适用
Investigation Into the Effects of Krill Oil vs. Fish Oil on Markers of Cardiovascular DiseaseMetabolic SyndromeNCT01705678Liverpool John Moores University19
招募中
不适用
Middle Age MuScle Krill StudySarcopeniaNCT06005064University of Glasgow92
招募中
不适用
The Krill Ageing Muscle Mechanisms (KAMM) StudySarcopeniaNCT06296875University of Glasgow80