T cell respons in legionella

Recruiting

• Conditions: Legionella disease; 10004018

• Registration Number: NL-OMON48272
• Lead Sponsor: Diakonessenhuis Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 270

Inclusion Criteria

(group1) Hospitalized Patients with a proven Legionella infection (positive Legionella urine antigen test/ culture/ PCR) of which a subgroup willing to participate to the follow up study
(group 2) healthy volunteers matched for age and gender
(group 3) Patients with clinical presentations of pneumonia and a proven other pathogen

Exclusion Criteria

• immunosuppressive medication
• < 18 years
• Incapacitated patients not able to give informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Diagnostic potential of the elispot to identify Legionella disease patients</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>To evaluate the T-cell respons in time in patients with a Legionella infection</p><br>