TCTR20200530002尚未招募1 期
Reduction in interleukin-5 and other eosinophil biomarkers by full-house endoscopic sinus surgery in the treatment of severe nasal polyps
Department of Otolaryngology, Faculty of medicine, Chulalongkorn University0 个研究点目标入组 20 人开始时间: 2020年5月30日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 0 N/A (No limit)（—）
- 性别
- All
入选标准
- •Any CRSwNP patient is defined as the presence of two or more symptoms for > 12 weeks, one of which should be:
- •either nasal blockage/obstruction/congestion or nasal discharge (anterior/posterior nasal drip)
- •Â± facial pain/pressure
- •Â± reduction or loss of smell
- •AND along with endoscopic and radiographic evidence of nasal polyps, grade ≥2 and diffuse bilateral mucosal inflammation
- •AND have indication for sinus surgery
- •**grade 0 being no visible polyps; grade 1 being polyps confined to the middle meatus; grade 2 being polyps beyond the middle meatus but not completely obstructing the nasal cavity; and grade 3 being polyps completely obstructing the nasal cavity
排除标准
- •1. prior sinus surgery
- •2. unilateral sinus changes
- •3. sinus disease associated with systemic conditions
- •4. under the age of 18
- •5. pregnant women
- •6. undertaking systemic and intranasal steroids and immunosuppressive medication during the past month
研究者
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