Effect of preoperative dexmedetomidine nebulisation on the hemodynamic response to laryngoscopy and endotracheal intubation in elective abdominal surgery under general anaesthesia.A prospective randomized control study at SMS Medical College Jaipur
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 94
- 试验地点
- 1
- 主要终点
- To determine systolic blood pressure,heart rate, diastolic blood pressure between the groups
研究概览
简要总结
Effect of pre operative dexmetomidine nebulisation on the hemodynamic response to laryngoscopy and endotracheal intubation in elective abdominal surgery under general anaesthesia.Upon arrival in operation theature the written informed consent pac and npo will be confirmed study population 94 wil be randomly divided in to two group by seal envelop method.group A 47 will receive dexmedetomidine 1 microgm kg total 4 ml ns and group B received nebulisation with normal saline 4 ml.then we will check hemodynamic parameter at different time of interval.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients body weight between 40-70 kg and elective surgery under general anesthesia and ASA grade 1 and 2.
排除标准
- •patient not willing to gave consent and patient with anticipated difficultairway and laryngoscopy time more than 15 seconds ,obese individual bmi more than 30kg per meter square and patirnt with known allergy to dexmedetomidine ,chronic disease hypertension DM ,Patient on beta blocker.
结局指标
主要结局
To determine systolic blood pressure,heart rate, diastolic blood pressure between the groups
时间窗: at just before laryngoscopy 1 3 5 7 9 11 15 30 45 min of intubation and just and 1 2 3 hrs of extubation
次要结局
- to asses sedation post operatively between the groups(to asses proportion of cases with complication)