Study of preoperative nebulisation of dexmedetomidine on response to laryngoscopy and endotracheal intubation in abdominal surgery under general anaesthesia

Phase 4

Not yet recruiting

• Conditions: Administration, (2) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2023/10/058469
• Lead Sponsor: Department of Anesthesiology SMS Medical College and Attached Hospitals Jaipur

Brief Summary

Effect of pre operative dexmetomidine nebulisation on the hemodynamic response to laryngoscopy and endotracheal intubation in elective abdominal surgery under general anaesthesia.Upon arrival in operation theature the written informed consent pac and npo will be confirmed study population 94 wil be randomly divided in to two group by seal envelop method.group A 47 will receive dexmedetomidine 1 microgm kg total 4 ml ns and group B received nebulisation with normal saline 4 ml.then we will check hemodynamic parameter at different time of interval.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-06-10
• Study Start: 2023-10-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 94

Inclusion Criteria

Patients body weight between 40-70 kg and elective surgery under general anesthesia and ASA grade 1 and 2.

Exclusion Criteria

patient not willing to gave consent and patient with anticipated difficultairway and laryngoscopy time more than 15 seconds ,obese individual bmi more than 30kg per meter square and patirnt with known allergy to dexmedetomidine ,chronic disease hypertension DM ,Patient on beta blocker.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine systolic blood pressure,heart rate, diastolic blood pressure between the groups	at just before laryngoscopy 1 3 5 7 9 11 15 30 45 min of intubation and just and 1 2 3 hrs of extubation

Secondary Outcome Measures

Name	Time	Method
to asses sedation post operatively between the groups	to asses proportion of cases with complication

Trial Locations

Locations (1)

SMS Hospital; 🇮🇳 Jaipur, RAJASTHAN, India

SMS Hospital

🇮🇳Jaipur, RAJASTHAN, India

Dr Anil Kumar Meena

Principal investigator

7976532973

anilkhokhar1995@gmail.com