Outcome of Dental Implant Therapy in Patients Treated With Antiresorptive Medication

Recruiting

• Conditions: Missing Teeth; Implants; Cancer; Osteoporosis

• Registration Number: NCT04741906
• Lead Sponsor: Copenhagen University Hospital at Herlev

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-1-21
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 225

Inclusion Criteria

Inclusion Criteria:<br><br> - Patient with cancer or osteoporosis, treated with antiresorptive treatment.<br><br> - The patients should have sufficient compliance, this includes willingness to have<br> the planned assessments<br><br> - The patient should have an expected life span at enrollment of at least 2 years.<br><br> - The local bone quality and quantity should be sufficient for implant insertion<br> without bone augmentation and is classified according to the classification by<br> Cawood & Howell 1988.<br><br>Exclusion Criteria:<br><br> - > 10 cigarettes daily<br><br> - HbA1c > 53 mmol/mol<br><br> - Poor oral hygiene<br><br> - Poor general condition: ECOG score 3 or 4.<br><br> - Poor prognosis: Expected survival <2 year is an exclusion cause.<br><br> - Presence of metastases of the liver brain.<br><br> - Poor local jaw bone quality acc. to Cawood classification stage 3 or 4.<br><br> - Unwillingness to comply with the planned assessments and recordings

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational [Patient Registry]
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dental implant survival;Dental implant survival;Dental implant survival;Dental implant survival;Dental Implant success;Absence of medical related osteonecrosis of the jaw (MRONJ)

Secondary Outcome Measures

Name	Time	Method
Oral Health Impact Profile;EORTC QLQ-H&N 35