Taste Test Between Desloratadine and Cetirizine Syrup in Children (Study P03829)(COMPLETED)
Phase 3
Completed
- Conditions
- Allergic Rhinitis
- Interventions
- Registration Number
- NCT00794378
- Lead Sponsor
- Organon and Co
- Brief Summary
This study was conducted to compare the taste acceptability of Zyrtec syrup with desloratadine syrup in children. Children between 6 and 11 years of age received 5 mL of each syrup, separated by 15 to 20 minutes on a single day.
- Detailed Description
This study is a cross-over study design.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 202
Inclusion Criteria
Subjects must be:
- Between 6 and 11 years of age in good general health
- Premenarcheal if female
Exclusion Criteria
Subjects who:
- Have known allergies or sensitivities to either of the drug formulations
- Have a medical condition that may interfere with the subject's ability to discriminate between tastes
- Have used any antihistamines within 24 hours prior to dosing
- Were taking sedatives, tranquilizers, or monoamine oxidase inhibitor drugs
- Were involved in another clinical or market research study within the past 30 days
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Desloratadine and Cetirizine Crossover Cetirizine (Zyrtec) To compare the preference in taste between desloratadine and cetirizine. Desloratadine and Cetirizine Crossover Desloratadine (Clarinex) To compare the preference in taste between desloratadine and cetirizine.
- Primary Outcome Measures
Name Time Method Taste acceptability as determined from smiley-face scale of 1 (frowning child) to 5 (happy child face). During the only study visit
- Secondary Outcome Measures
Name Time Method Taste flavor preference between bubble-gum, banana-grape, or grape flavors During the only study visit Adverse Events During the only study visit