Erector Spinae Plane Block Versus Modified Thoracolumbar Interfascial Plane Block

Not Applicable

• Conditions: Achievement of High-quality Analgesia, Rapid Recovery With Rehabilitation in Lumber Spine Discectomy
• Interventions: Drug: Regional Anesthetic Injection

• Registration Number: NCT06910696
• Lead Sponsor: Zagazig University

Brief Summary

the purpose of this study is to compare of better postoperative analgesia following lumber spine discectomy

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-03-19
• Study First Submitted QC: 2025-03-27
• Status Verified: 2025-04
• Study First Posted: 2025-04-04
• Study Start: 2025-04-11
• Last Update Submitted: 2025-04-11
• Last Update Posted: 2025-04-15
• Primary Completion: 2025-09-01
• Study Completion: 2025-12-01

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 144

Inclusion Criteria

• Written informed consent from the patient.
• Physical status: ASA 1& II.
• BMI = (25-30 kg/m2).
• Type of operation: elective Lumbar discectomy .

Exclusion Criteria

• Altered mental state.
• Patients with known history of allergy to study drugs.
• Advanced hepatic, renal, cardiovascular, and respiratory diseases.
• Patients with chronic pain.
• Patients receiving anticoagulants.
• Contraindications of regional anesthesia, e.g., allergy to local anesthetics, coagulopathy, or septic focus at site of injection.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
(mTLIP )Group	Regional Anesthetic Injection	Patients will receive 20 mL of 0.25% bupivacaine on each side through Modified thoracolumbar interfascial block
(ESPB) Group	Regional Anesthetic Injection	Patients will receive 20 mL of 0.25% bupivacaine on each side through Erector spinae block

Primary Outcome Measures

Name	Time	Method
Length of hospital stay	up to 1 weak postoperative.	from the day of admission till discharge from hospital

Secondary Outcome Measures

Name	Time	Method
The recovery time	up to 30 minutes postoperative.	time from discontinuation of isoflurane to first response to verbal command
Functional reach test	24 hours postoperative	quantifies participants' dynamic in-place standing balance control to reach distance. The distance between the starting and maximal forward reach distance beyond the participant's arm length represents the reach distance and is recorded in centimeters
Pain intensity	30 minutes after the end of the surgery, as well as 3, 6, 12, and 24 hours postoperatively	10-point NRS \[(0 = no pain, 10 = worst imaginable pain), 1 - 3: Mild pain (nagging, annoying, slightly interfering with activities of daily living (ADLs), 4 - 6: Moderate pain (significantly interfering with ADLs, 7 - 10: Severe pain (disabling, unable to perform ADLs)\]
The time of discharge	up to 2 hours postoperative.	The time from arrival to the PACU to discharge to the ward
6 minutes walk test	24 hours postoperative	involves walking for 6 min on a 30 m walking path and measuring the distance
Time up and go test	24 hours postoperative	objective measure of functional disability that can be used to evaluate various activities such as standing, accelerating, walking, decelerating, and turning, which are often limited in patients with lumbar degenerative diseases
Time to first call analgesia	24 hours postoperative
Total naluphine consumption	24 hours post-operative

Trial Locations

Locations (1)

faculty of medicine,zagazig university Egypt Ext. 002 K.Howida@yahoo.com; 🇪🇬 Zagazig, Egypt