Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke
Completed
- Conditions
- Test the Efficacy of Antiplatelet Regimes in Acute Stroke
- Registration Number
- NCT01273935
- Lead Sponsor
- Ruhr University of Bochum
- Brief Summary
The aim of this study is to evaluate the low-response prevalence of early antiplatelet therapy and to test the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).
- Detailed Description
Antiplatelet agents are important therapeutic options in treating patients with acute ischemic strokes to prevent recurrent ischemic events or death. The aim of this study was to evaluate the low-response prevalence of early antiplatelet therapy and the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
- suspected acute cerebrovascular ischemic events and patients who were admitted to the stroke unit where antiplatelet therapy was initiated
Exclusion Criteria
- severe liver disorders, current gastrointestinal disorders, congestive heart failure, life-threatening malignancies and a personal or family history of bleeding disorders
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Result of platelet function test Aggregometry result of antiplatelet therapy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Neurology, St. Josef - Hospital, Ruhr-University
🇩🇪Bochum, NRW, Germany