A study of drugs given in hypertension and evaluation of cardiovascular risk in hypertensive post-menopausal women

Phase 4

Completed

• Conditions: HYPERTENSION

• Registration Number: CTRI/2017/06/008779
• Lead Sponsor: Govt Medical College Patiala

Brief Summary

The present study is designed toinvestigate the prescribing patterns of anti- hypertensive drugs and scoring ofcardiovascular risk in hypertensive post-menopausal women (PMW) in atertiary care teaching hospital in Patiala. This is an observational andcross-sectional prospective study to be conducted on the PMW attending theCardiology Outpatient Department of Rajindra Hospital over a period of 1 year.All the prescriptions prescribed to PMW for hypertension will be surveyed forone point analysis. Questionnaires, measurements and blood biochemical indiceswill be collected. The cardiovascular risk for next 10 years will be calculatedfor each patient using Framingham’s cardiovascular risk calculator using BodyMass Index (BMI) as per the online equation. Data collected from survey will beanalyzed for patterns of drug use and 10 year cardiovascular risk.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-04-01
• Last Update Posted: 2017-05-26

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 300

Inclusion Criteria

• Inclusion Criteria 1 Women with self reported cessation of menstruation for more than 12 consecutive months.
• 2PMW with surgically induced menopause.
• 3Patients with HT in stage I/ stage II.
• 4Newly diagnosed and old patients of HT.
• 5Hypertensive patients with or without comorbidities like diabetes, obesity, hypothyroidism.
• Exclusion Criteria 1Women with indeterminate menopausal status.
• 2Patients with SBP > 210 and/or DBP > 120 mm Hg, requiring emergency care.
• 3Patients with CAD at present or previous history of CAD.
• 4Patients with chronic renal or hepatic disease.

Exclusion Criteria

• Inclusion Criteria 1 Women with self reported cessation of menstruation for more than 12 consecutive months.
• 2PMW with surgically induced menopause.
• 3Patients with HT in stage I/ stage II.
• 4Newly diagnosed and old patients of HT.
• 5Hypertensive patients with or without comorbidities like diabetes, obesity, hypothyroidism.
• Exclusion Criteria 1Women with indeterminate menopausal status.
• 2Patients with SBP > 210 and/or DBP > 120 mm Hg, requiring emergency care.
• 3Patients with CAD at present or previous history of CAD.
• 4Patients with chronic renal or hepatic disease.
• •Women with indeterminate menopausal status.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluate the prescription trends of anti-hypertensive drugs in PMW.	Single observation at the time of inclusion in the study

Secondary Outcome Measures

Name	Time	Method
Evaluate the 10 year cardiovascular risk in PMW so that high risk PMW can be identified.	Single observation at the time of inclusion in the study

Trial Locations

Locations (1)

Dept of Cardiology; 🇮🇳 Patiala, PUNJAB, India

Dept of Cardiology

🇮🇳Patiala, PUNJAB, India

Dr Ritika Singla

Principal investigator

9041821352

apurba.cnmc03@gmail.com