Flow Controlled Ventilation in Robot-assisted Laparoscopic Surgery

Not Applicable

Not yet recruiting

• Conditions: Mechanical Ventilation Complication; Postoperative Pulmonary Atelectasis

• Registration Number: NCT06256900
• Lead Sponsor: Cantonal Hospital of St. Gallen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-1-29
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Not yet recruiting
• Sex: All
• Target Recruitment: 774

Inclusion Criteria

Inclusion Criteria:<br><br> - Patient undergoing elective robot-assisted laparoscopic surgery (either abdominal,<br> urologic or gynecologic surgery) with a duration of expected ventilation of = 90<br> minutes<br><br> - Male or female aged = 18 years<br><br> - ASA Physical Status Classification System score I - III<br><br> - Must be willing and able to give written informed consent to participate in the<br> study and agree to comply with the study protocol prior to initiation of any<br> study-mandated procedure and study intervention<br><br>Exclusion Criteria:<br><br> - Patient with weight < 40 kg ideal body weight<br><br> - ASA Physical Status Classification System score IV - VI<br><br> - Previous enrolment into the current study<br><br> - Enrolment of study investigator, his/her family members, employees and other<br> dependent persons<br><br> - If female and of childbearing potential: known pregnancy or a positive urine<br> pregnancy test (confirmed by a positive serum pregnancy test), or lactating

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Differences in the number of patients developing postoperative pulmonary complications

Secondary Outcome Measures

Name	Time	Method
Differences in Clara-Cell 16 serum concentrations;Differences in area under the curve of postoperative modified Horovitz index;Differences in end-tidal to capillary/arterial CO2 gradient;Differences in minimal required intraoperative FiO2 concentration;Differences in parameters derived from the electrical impedance tomography;Differences in perioperative ventilation/oxygenation parameters