NCT00033072Unknown1 期
Assessment of Potential Interactions Between Intravenous Methamphetamine and Oral Selegiline
适应症
相关药物
试验速览
- 阶段
- 1 期
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- pharmacokinetic assessment
研究概览
简要总结
The purpose of this study is to assess the potential interactions between intravenous methamphetamine and oral selegiline.
详细描述
To determine the safety of the selegiline concurrent with d-methamphetamine challenges of 15mg & 30mg i.v. with the focus being on cardiovascular responses (HR,BP) to the i.v. methamphetamine challenges. This is a randomized, single-blind, placebo-controlled, two-arm study design to evaluate the safety of selegiline treatment, compared to placebo treatment, concurrent with i.v. methamphetamine challenges.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 主要目的
- Treatment
- 盲法
- Single
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Volunteers who meet DSM-4 criteria for methamphetamine abuse or dependence; non-treatment seeking individuals
- •Be able to verbalize understanding of consent form; provide written informed consent
排除标准
- •Please contact site for more information
结局指标
主要结局
pharmacokinetic assessment
safety of selegiline
次要结局
未报告次要终点
研究者
研究点 (2)
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