Clinical Trials/NCT00265278

NCT00265278

Unknown

Phase 1

Double-Blind, Placebo-Controlled Assessment of Interactions Between Intravenous Methamphetamine and Modafinil

National Institute on Drug Abuse (NIDA)1 site in 1 country16 target enrollmentMarch 2005

ConditionsAmphetamine-Related Disorders

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Amphetamine-Related Disorders
Sponsor: National Institute on Drug Abuse (NIDA)
Enrollment: 16
Locations: 1
Primary Endpoint: Cardiovascular
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to assess the potential interactions between intravenous methamphetamine and oral Modafinil.

Detailed Description

The primary aims of this experiment are to determine if there are significant safety interactions between oral modafinil and intravenous methamphetamine. Safety will be assessed by measuring adverse events and cardiovascular responses of heart rate (HR), blood pressure (BP), and electrocardiogram (ECG) and stroke distance (ICG).

Registry

clinicaltrials.gov

Start Date

March 2005

End Date

March 2006

Last Updated

9 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

National Institute on Drug Abuse (NIDA)

Eligibility Criteria

Inclusion Criteria

•normotensive
•good physical and mental health
•body mass index between 18 and 30
•if female, using an acceptable method of contraception and are not pregnant
•able to give voluntary informed consent

Exclusion Criteria

•Please contact site for further details

Outcomes

Primary Outcomes

Cardiovascular

Subjective symptoms/Mood Effects

Study Sites (1)

Loading locations...

Similar Trials

Assessment of Potential Interactions Between Methamphetamine and Bupropion - 1Amphetamine-Related Disorders

NCT00040040National Institute on Drug Abuse (NIDA)20

Assessment of Potential Interactions Between Methamphetamine and Selegiline - 1Amphetamine-Related Disorders

NCT00033072National Institute on Drug Abuse (NIDA)16

Assessment of Interactions Between Methamphetamine and Aripiprazole - 1Amphetamine-Related Disorders

NCT00089440National Institute on Drug Abuse (NIDA)17

A Phase 1 Parallel-Group, Double-Blind, Placebo-Controlled Cardiovascular and Behavioral Study Assessing Interactions Between Single Doses of Oral Reserpine and Intravenous Methamphetamine - 1Amphetamine-Related Disorders

NCT00267657National Institute on Drug Abuse (NIDA)30

Methylphenidate and Driving Ability in Adult Patients With Attention-Deficit Hyperactivity DisorderADHD

NCT00223561Utrecht Institute for Pharmaceutical Sciences18