Pharmaceutical enhancement of complex problem-solving in healthy adults

Phase 4

Completed

• Conditions: Cognitive enhancement; Mental Health - Studies of normal psychology, cognitive function and behaviour; Neurological - Studies of the normal brain and nervous system

• Registration Number: ACTRN12617001544369
• Lead Sponsor: The University of Melbourne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-11-07
• Last Update Posted: 12 November 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Healthy volunteers aged between 18 and 35 years old.

Exclusion Criteria

History of psychiatric or neurological illness including epilepsy, head injury, previous use of psychotropic medication, history of significant drug use, heart conditions (including high blood pressure, defined as above 140 mm/Hg systolic and/or 90 mm/Hg diastolic pressure as measured at the initial assessment session) pregnancy, or glaucoma. Any family history of sudden death of a first degree relative through cardiac or unknown causes before the age of 50 years old will also exclude the participant.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Performance in complex optimisation task as measured by accuracy scores. That is, are the items selected by the participant included in the optimal solution. This is also referred to as computational perfomance.[Tasks will be administered 90 minutes after drug administration, and completed by 180 minutes after drug administration. This outcome will be assessed for each drug administration.]