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The Effects of testosterone supplementation on functional mobility, quality of life, body composition, cognitive function, aortic stiffness and cardiovascular risk factors, and bone mineral density in ageing men with an age-related decline of testosterone.

Completed
Registration Number
NL-OMON21427
Brief Summary

JAMA. 2008 Jan 2;299(1):39-52.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
240
Inclusion Criteria

Men with testosterone level below the 50th percentile cut-of point (study population-based testosterone distribution) and age > 60 years.

Exclusion Criteria

1. Severe diseases or conditions interfering with conduct of study;

2. Conditions for which increase of androgen-like substances are contra-indicated;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Functional Mobility and Quality of Life.
Secondary Outcome Measures
NameTimeMethod
Body Composition, Cognitive Function, Aortic Stiffness and Cardiovascular Risk Factors, Bone Mineral Density and Safety (Prostate, Liver Enzymes and Haematological Parameters).
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