Evaluation of Postoperative Analgesia with Intrathecal Morphine after Laparoscopic or Robotic Nephrectomy

Anshuman Sarkar0 个研究点目标入组 62 人开始时间: 待定最近更新: 2024年5月27日

试验速览

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•1. Patients who will undergo elective laparoscopic or robotic radical nephrectomy
•2.American society of Anaesthesiology Physical Score- I-III

•1. Emergency surgery
•2. Conversion to open procedure
•3. Contraindications to spinal anaesthesia (Paient refusal,spinal deformities,local site infection, severe aortic stenosis, increased intrcranial pressure)
•4. Contraindications to study medication (allergy to Morphine, Bupivacaine)
•5. Body mass Index more than 30 kg/m2 or those with documented obstructive sleep apnoea
•6. Patients with life threatening arrhythmias
•7. Patients with left ventricular ejection fraction <40%
•8. Acute myocardial infarction (within 30 days)
•9. Acute pulmonary edema (within 7 days)
•10. Chronic obstructive pulmonary disease with a forced expiratory volume (FEV1) in the first second of expiration <50%
•11. Coagulopathy (Platelet <1 lakh/cumm, APTT >2 times than control, INR >1.5)
•12. Pre existing neurological illness (history of strokewithin last 6 months or with residual focal neurological deficits, history of low back pain with radiculopathy)
•13. Significant liver dysfunction (liver enzymes >3 times of normal)
•14. Significant renal dysfunction (Creatinine >2 times normal)
•15. Psychiatric illness that will make the patient unable to understand numeric rating scale (NRS) or use of patient controlled analgesia pump (PCA)
•16. Opioid abuse
•17. Patient receiving systemic opioids for chronic pain

发起方

Anshuman Sarkar