The Effects of Aerobic Exercise Training on Cardiorespiratory Fitness in Stroke Patients

Not Applicable

Completed

• Conditions: Stroke, Cardiovascular

• Registration Number: NCT05058586
• Lead Sponsor: Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Brief Summary

Background:

Aerobic exercise training has favorable effects on quality of life, motor recovery, and aerobic endurance after stroke.

Objectives: In this study, the investigators aimed to explore the effects of anti-gravity treadmill gait training and underwater walking therapy on cardiorespiratory fitness in stroke survivors.

Detailed Description

Methods: Seventy patients with a history of stroke were admitted to our center between July 2017 and January 2018. Subjects who participated in the study were randomly assigned to anti-gravity treadmill training, underwater walking therapy, and control group. Investigators examined the aerobic capacity of participants by using the 6-minute walk test and cycle ergometer testing before starting the treatment along with a one-month follow-up. The patient's balance was examined by using the Berg Balance Scale (BBS).

Study Timeline

• Study Start: 2017-07-01
• Primary Completion: 2018-01-31
• Study Completion: 2018-01-31
• Study First Submitted: 2021-08-25
• Status Verified: 2021-09
• Study First Submitted QC: 2021-09-16
• Last Update Submitted: 2021-09-16
• Study First Posted: 2021-09-27
• Last Update Posted: 2021-09-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients between the ages of 18 and 80 and diagnosed with stroke and time from stroke onset to admission were longer than three months
• Independent walking ability more than 10 meters with or without assistance
• Patients whose cognitive and functional status were suitable for the training program

Exclusion Criteria

• Had a previous history of stroke
• Bilateral hemiplegia
• Leg-length difference >2.0 cm
• Fixed flexion contracture or severe joint deformity
• Bladder or bowel incontinence
• Open wound
• Cardiovascular complaints and can not tolerate exercise training
• Other neurological comorbidities including, multiple sclerosis (MS), spinal cord injury (SCI), traumatic brain injury (TBI), Parkinson's disease, and intracranial tumors
• Congestive heart failure
• Atrial fibrillation (AF), use of antiarrhythmic drugs affecting QT duration, any type of bundle branch block on electrocardiogram (ECG)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Cycle ergometer training	Change from baseline VO2 max at 4 weeks	VO2 max
6-minute walk test	Change from baseline length of walking distance at 4 weeks	Length of walking distance

Trial Locations

Locations (2)

Konya City Hospital; 🇹🇷 Meram, Konya, Turkey

Gaziler Physical Theraphy and Rehabilitation; 🇹🇷 Ankara, Turkey