preparation for delivery in late pregnancy
Not Applicable
- Conditions
- Disorders related to long gestation and high birth weightvaginal Isosorbaid mononitrat and vaginal estradiol and Placebo effect on cervix ripening.
- Registration Number
- IRCT2015053122507N1
- Lead Sponsor
- Deputy Director of Research and Technology of Ardabil University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 99
Inclusion Criteria
singleton pregnancy; cephalic presentation; intact membranes; BS less than 6; the result of normal fetal health monitoring; lack of uterine contractions; the absence of systemic problems in the history; clinical examination; age 15 to 35
Exclusion criteria: women with preeclampsia; history of previous cesarean; active genital herpes; poly Hydramnious; placenta previa or placental abruption risk; membrane rupture; history of Cardiac or respiratory disease; the presence of any contra indication for labor induction; systolic blood pressure less than 90 mmHg
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bishop score (cervix ripening). Timepoint: at the visit, 12 hours and 24 hours later. Method of measurement: Vaginal examination (According to Williams reference table to determine the Bishop score).
- Secondary Outcome Measures
Name Time Method From active phase to full dilatation. Timepoint: During the study. Method of measurement: Observation and examination.;From full dilatation to delivery. Timepoint: During the study. Method of measurement: Observation and examination.;From Induction to active phase. Timepoint: During the study. Method of measurement: Observation and examination.;Delivery. Timepoint: During the study. Method of measurement: Observation and examination.;Maternal side effects (headache, nausea, vomiting, and dizziness). Timepoint: During the study. Method of measurement: Observation and examination.;The consequences of neonatal (first and fifth minute Apgar score, gender and birth weight, infant hospitalized in the Intensive Care Unit, Meconium defecation). Timepoint: During the study. Method of measurement: Observation and examination.