The use of vaginal iso sorbide mononitrate to make the uterine cervix more favourable for induction of labour
Not Applicable
- Conditions
- Effects of vaginal Iso Sorbide Mononitrate (ISMN) for pre induction cervical ripening
- Registration Number
- SLCTR/2007/009
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow up complete
- Sex
- Not specified
- Target Recruitment
- 156
Inclusion Criteria
Consecutive women with uncomplicated singleton pregnancies with cephalic presentation between 40 weeks + 5 days to 41 weeks of period of amenorrhea where the dates have been confirmed by an early ultrasound scan and having a modified Bishop score 5
Exclusion Criteria
Subjects with any medical or obstetric complications or any contraindication for the use of ISMN will be excluded
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pulse Rate, Blood Pressure, Resistance Index, Pulsatality Index at 180 & 360 minutes & 48 hrs ,Modified Bishop Score at 375 minutes Cardiotocographs and Fetal Acoustic Stimulation Test results ,proportions establishing Spontaneous labour or becoming favourable for induction of labour or needing caesarean section within 48 hrs of the therapy ,and mode of delivery, interval and the five minute Apgar Scores of babies delivered within 72 hours of initial therapy []<br>
- Secondary Outcome Measures
Name Time Method Side effects of the ISMN ( headache, nausea, palpitations, hot flushes, abdominal pain, pelvic pain ) []<br>