A Comparative Study On The Effect Of Propolis And Dentine Bonding Agent In Treating Dentine Hypersensitivity
- Conditions
- Dentine Hypersensitivity
- Interventions
- Drug: Dentin-Bonding Agents
- Registration Number
- NCT04754763
- Lead Sponsor
- Dow University of Health Sciences
- Brief Summary
Background:
Dentine hypersensitivity (DH) causes considerable pain and discomfort to an individual due to number of stimuli on exposed dentine. Different kinds of treatment strategies are used in the resolution of dentine hypersensitivity including the use of propolis and dentine bonding agent. No study had compared the efficacy of propolis and dentine bonding agent.
Objective:
The objective of the study was to find out whether there is a difference in the efficacy of Propolis and seventh generation dentine bonding agent in reducing the dentine hypersensitivity. Comparison within the groups and pairwise comparisons were also recorded in reducing dentine hypersensitivity.
Methods:
In this six month In- Vivo single blinded randomized clinical study, a total number of 52 patients with complain of dentine hypersensitivity were selected in two groups after taking informed consent. Group A and B received 30% ethanolic extract of propolis and dentine bonding agents respectively by a trained operator. Recordings of dentine hypersensitivity were obtained at Day 0, before and after the application of experimental agents, and also on Day 7, 15 and 30 by the principal investigator. Response was measured by Visual Analog Scale and Schiff Cold Air Sensitivity Scale. Statistical Package for the Social Sciences (SPSS) version 20 was used to analyze the data with level of significance set at p \< 0.05. Friedman test was applied to see the comparison within groups and Wilcoxon Signed Rank test was used for Pairwise comparison. Mann Whitney U-Test was applied for comparison between groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 52
- Outpatients reporting to Periodontology department of Dow International Dental College (DIDC) with dentine hypersensitivity
- Patients having age of 20- 45 years
- Systemically healthy patients
- Patients having at least 2 vital teeth with hypersensitivity
- Patients having sensitivity on facial surfaces to air stimulus
- Patients with Score I of Silness and Loe Plaque Index 77
- Patients who used Fluoride dentifrices for hypersensitivity but could not get relief from it.
- Patients with carious, cracked or restored teeth, abutment teeth used of removable or fixed prosthesis and tooth with any other dental pathology
- Patients who used analgesics, mood alteration drugs during last six months
- Smoker, pregnant and nursing mothers
- Patients who used tooth whitening or bleaching agents in the last six months
- Patients who were undergoing orthodontic therapy and history of periodontal surgery during last six months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Seventh generation Dentine Bonding Agent (Scotchbond™ Universal Adhesive, 3M ESPE) Dentin-Bonding Agents Application of Seventh generation Dentine Bonding Agent (Scotchbond™ Universal Adhesive, 3M ESPE) on sensitive surfaces was applied single coated for 20 seconds, gently applied air for 5 seconds and cured for 10 seconds (as per manufacturer's instructions). Followup was done at 7th, 15th and 30th day Propolis Propolis Propolis was applied by disposable micro brush on particular sensitive teeth and left undisturbed for 60 seconds to let it dry. Followup was done at 7th, 15th and 30th day
- Primary Outcome Measures
Name Time Method Effect Of Propolis And Dentine Bonding Agent In Treating Dentine Hypersensitivity Day 30 Treatment of dentine hypersensitivity assessed with the help of Schiff Cold Air Sensitivity Scale. Recordings were obtained on Day 30.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Dow International Dental Campus (Defence Campus)
🇵🇰Karachi, Sindh, Pakistan