Does the time between the production of semen and Intra-Uterine Insemination has an impact on pregnancy rates? A prospective randomized clinical trail.

Completed

• Conditions: subfertiliteit; insertion of sperm into the womb; Intrauterine insemination

• Registration Number: NL-OMON45103
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 254

Inclusion Criteria

Patients who start their first IUI treatment. All subsequent cycles fall within this study.
Patients who start a new IUI treatment after an ongoing pregnancy.
Both IUI performed in a natural cycle and stimulated cycles fall within this study.
Patients with well-adjusted, non-endocrine hormonal pathology fall within this study.

Exclusion Criteria

Patients who have IUI with donorsemen.
Patients in which the semen was obtained in a different way than masturbation (bladder irrigation, electrical stimulation).
Patients who have less than 0.5 million progressive motile sperm left over after work-up of semen.
Patients with polycystic ovarian syndrome (PCOS).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Ongoing pregnancy rate per patient couple (positive fetal cardiac activity 10<br /><br>weeks after IUI).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Clinical pregnancy rate per IUI cycle (HCG> 50 IU /l at 16 days after IUI).<br /><br>Ongoing pregnancy rate per IUI cycle (positive fetal cardiac activity 10 weeks<br /><br>after IUI).<br /><br>Percentage multiple pregnancies<br /><br>Percentage biochemical pregnancies and abortions<br /><br>Percentage/number of live births</p><br>