Correlation of Intraocular Pressure With Intracranial Pressure in Childs With Severe Trauma Brain Injury
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Intraocular pressure smaller than 20 mmHg
研究概览
简要总结
Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend).
Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values.
详细描述
Severe Trauma Brain Injury (TBIs) is a public health problem and monitoring of Intracranial Pressure (ICP) is a determinant key of it prognosis. Within the noninvasive methods to estimate the ICP, the measurement of intraocular pressure has been proposed because of its biological plausibility (proximity of the eye to the encephalic contend).
Objective. Correlate intraocular pressure with ICP in children with TBIs and obtain their utility values.
Material and methods. Correlation and diagnostic test design study. Inclusion criteria: children with TBIs admitted to the emergency room and indication of catheter for ICP measurement.
Exclusion criteria: injury or ophthalmic disease, glaucoma, encephalic death. Intraocular pressure was measured with electronic tonometer in both eyes prior to placement of the catheter for ICP measurement.
Correlation was estimated with Spearman's Rho. The utility values of the diagnostic test were obtained from an Receiver Operating Characteristic curve.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 2 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children with severe trauma brain injury (Coma Glasgow Scale smaller than 9 points),
- •who have been admitted to the pediatric emergency room
- •and in whom the treating neurosurgeon has decided to place a catheter for intracranial pressure measurement.
排除标准
- •Ocular trauma,
- •brain death,
- •know eye disease,
- •refusal of parents or guardians to participate in the study.
结局指标
主要结局
Intraocular pressure smaller than 20 mmHg
时间窗: Immediately
Abscence of increased intraocular pressure (smaller than 20 mmHg) without intracranial pressure smaller than 20 mmHg.
次要结局
- Intraocular pressure equal or more than 20 mmHg(Immediately)
研究者
KARLA ISIS AVILES MARTINEZ
Dra. Karla Isis Avilés-Martínez
Hospital Civil de Guadalajara