Optisch spectraal transmissie voor therapie monitoring en correlatie met arteriële vaatstijfheid bij patiënten met reumatoïde artritis die gaan starten met TNF remmende therapie
Recruiting
- Conditions
- Rheumatoid arthritis,Cardiovascular disease
- Registration Number
- NL-OMON20387
- Lead Sponsor
- Reade Center for Rehabilitation and Rheumatology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
18 years or older
- Active rheumatoid arthritis in hands or wrists, defined as ≥ 2 swollen hand joints (IP, PIPs and/or MCPs) or ≥ 1 swollen wrist joints
Exclusion Criteria
- Surgery in wrist or hand in the preceding 3 months
- Other active concomitant musculoskeletal disease
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main study parameters are the results from the handscan measurement, arterial stiffness as measured with pulse wave velocity and augmentation index, DAS28 and the ultrasound assessment of the hand joints at all time points.
- Secondary Outcome Measures
Name Time Method