Treatment of ocular surface with HD-AM

Phase 1

Recruiting

• Conditions: Refractory eyes surface disease

• Registration Number: JPRN-jRCTs042190030
• Lead Sponsor: Hayashi Atsushi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-27
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

1)1:Pterygium/including Scleral malacia/Conjunctival tumor(Intraconjunctival hyperplasia), 2:Corneal perforation/Conjunctival perforation, 3:Glaucoma bleb leak/Glaucoma bleb scarring, 4:Corneal/conjunctival epithelial defect (including Corneal scar, induced by the Corneal transplantation), 5:Symblepharon adhesion (including Stevens-Johnson Syndrome, Pemphigoid of the eye, Thermochemical trauma scar, heavy Scarring keratoconjunctival disease)
2) more than 20 years-old
3)The patients with relatively good general condition
4) The patients whom it is judged to be available for observation, the testing that conformed to a study enforcement plan and a survey.

Exclusion Criteria

1)The patients whom a doctor judg ed safely for study period if it was difficult hospital visiting and to come home.
2)The patients who complicate eye infection with activity.
3)The patients who plan the enforcement of eye operations for evaluation eyes effective during study period in (we assume the ag reement acquisition study initiation).
4)one eyes are the patients of enucleation eyes or evisceration eyes.
5)For the g roup medicine of the planned drug(dropping lotion in the eyes anesthetic ag ent, fluorescein) to use during study period, it is the patients with a history of the drug allergy.
6)The patients (saying that, however, the subjects who do not receive the study drug are possible) who participated in other studies or clinical studies within six months.
7) Preg nancy or the childbearing patients who may be preg nant or hope for preg nancy during study period or do not use appropriate contraception.
8) Patients who can be entried Advanced Medical B (jRCTs 042180103).
9)The patients who were judg ed to be inadequate as an object of this study in testing at agreement acquisition by doctor.

Study & Design

• Study Type: Interventional
• Study Design: Not specified