Comparison of age-differentiated incidence of sympathetic stimulation effect from rapid increases in desflurane concentration during induction of anesthesia with propofol and remifentanil; prospective randomized single-blind clinical investigatio
- Conditions
- Not Applicable
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 400
Patients, who are aged 20-59 years and to be scheduled for spine surgery in Severance Hospital, Seoul, Republic of Korea, are to be recruited.
Patients who are anticipated to have difficulty for endotracheal intubation, presenting with upper respiratory infection or asthma, have a comorbidity of cardiovascular, cerebrovascular or neuronal, renal or endocrinologic abnormality, and are diagnosed with metastatic cancer, except for patients with well-controlled hypertension or diabetes with oral agents. Vulnerable subjects, such as pregnant women, illiteracy or foreigners, are also excluded.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method heart rate
- Secondary Outcome Measures
Name Time Method Arterial blood pressure - systolic, diastolic and mean