Gonadotropin-releasing hormone (GnRH) agonist for prevention of chemotherapy induced menopause in malignant ovarian germ cell tumor: a multicenter study
Not Applicable
Recruiting
- Conditions
- Diseases of The genitoruinary system
- Registration Number
- KCT0003286
- Lead Sponsor
- Bundang CHA General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 65
Inclusion Criteria
1) Patients diagnosed as pathologically malignant germ cell tumors of the ovary. Patients who received
at least one ovarian conserved chemotherapy
2) Patients 12 years old (after menarche) ~ 40 years old
Exclusion Criteria
1) Post menpausal women
2) Premenstrual girl
3) Patients with menopause induced by surgery or radiation therapy prior to chemotherapy
4) Patients diagnosed with other carcinoma and underwent chemotherapy and pelvic radiation therapy
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of early menopause induced by chemotherapy
- Secondary Outcome Measures
Name Time Method Age of menopause, pregnancy rate and side effects of GnRH agonist