Antagonist versus agonist protocols: in patients with polycystic ovary syndrome treated for ICSI cycles

Not Applicable

• Conditions: Fertility-female; Infertility in PCOS patients

• Registration Number: PACTR201411000933365
• Lead Sponsor: Obestetrics and Gynaecology Department, Faculty of Medicine, University of Alexandria

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-11-08
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Other
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

1. Normogonadotrophic females ( tubal factor ¿ unexplained infertility)
2.PCOS patients fulfilling roterdam criteria of PCOS). Diagnosis depends on two of the following criteria only:
Clinical and/or biochemical evidence of hyperandrogenism with exclusion of other causes of androgen excess.
Oligo or anovulation.
Polycystic ovaries by ultrasound(ovarian volume>12cc with 10 or more cysts 2-
8mm in diameter arranged around echo
3.Body mass index(BMI)<35.

Exclusion Criteria

critria:1.Hypogonadotrophic patients
2. Hypergonadotrophic patients.
3.BMI>35 4.Endometriosis
5.Poor response in previous ICSI cycles 6.uterine factor infertility.
7.Severe male factor infertility. 8.History of ovarian surgery.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total number of oocytes;The number of mature oocytes per cycle of induction;Serum estradiol and progesterone level on the day of HcG.;Implantation rate(number of sacs per number of embryo transfer).

Secondary Outcome Measures

Name	Time	Method
Clinical pregnancy