Randomized Controlled Trial of Core Stability Training in Patients With Multiple Sclerosis: Biomechanical and Performance Based Analysis of Gait
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Multiple Sclerosis
- Sponsor
- Hacettepe University
- Enrollment
- 68
- Primary Endpoint
- 6 Minutes Walk Test
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Gait and mobility are among the functions frequently affected in Multiple Sclerosis (MS) and have a negative impact on quality of life. Strength losses in lower limb muscles, ataxia, sensory problems and fatigue are the most important reasons of walking problems in patients with MS. In addition to loss of strength and tonus problems, especially biomechanical disorders can be seen on foot and this problem affects gatin and balance negatively. The stabilizing muscles, defined as the "core" region and enveloping the body like a corset, are active in the context of postural preparation prior to lower extremity movements and stabilize for the limb movements to be performed. The aim of this study was to investigate the effects of spinal stabilization exercises on walking performance, fatigue, plantar pressure distribution, balance, muscle strength and quality of life in patients with Multiple Sclerosis.
Investigators
Baris Cetin
Research Assisstant
Hacettepe University
Eligibility Criteria
Inclusion Criteria
- •Older than 18 years old
- •EDSS score is between 3-5,5
- •Patients who did not take corticosteroid therapy within three months
- •Patients who get at least 24 points from the Mini Mental Test were included in the study.
Exclusion Criteria
- •Patients who had an acute MS attack or had an attack within the last three months.
- •An orthopedic or systemic problem that would prevent participation in exercises
- •Patients who were using walking orthoses or walking aids were not included in the study.
Outcomes
Primary Outcomes
6 Minutes Walk Test
Time Frame: Change from Baseline 6 Minutes Walking Distance at 6 weeks.
Maximum Walking Distance in 6 Minutes
Plantar Pressure Distribution
Time Frame: Change from baseline peak pressure and contact area values at 6 weeks
Contact area values of 10 subregions under the foot
Modified Borg Scale
Time Frame: Change from Baseline Fatigue Score at 6 weeks.
Evaluating fatigue between the scores of 0 and 10. "0" means no fatigue at all. "10" means maximal fatigue.
Multiple Sclerosis Quality of Life Scale
Time Frame: Change from baseline mental and physical quality of life scores at 6 weeks
Quality of life assessment with 54 questions about mental and physical health in daily life activities.
Secondary Outcomes
- Muscle strength with hand held dynamometer(Change from baseline muscle strength at 6 weeks)
- MiniBESTest(Change from baseline MiniBESTest scores at 6 weeks)
- Dynamic Gait Index(Change from baseline Dynamic Gait Index scores at 6 weeks)