Overlapping Pain Trajectory Study
- Conditions
- MigraineMusculoskeletal PainChronic PainWidespread Chronic PainLow Back PainHealthy VolunteersFunctional Abdominal Pain Disorders
- Registration Number
- NCT05752396
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria:<br><br> 1. General Criteria<br><br> - Access to the internet either by laptop, tablet, or phone (for REDCap Surveys)<br><br> - English-speaking<br><br> - Parent or guardian willing to comply with protocol, complete study assessments,<br> and provide written informed consent<br><br> 2. Control Specific Criteria<br><br> - No history/active chronic pain<br><br> 3. Patient Specific Criteria<br><br> - Patients will need a diagnosis of a chronic pain derived congruent with ICD-11<br> criteria related to headache (migraine, daily headache), abdominal (FAPD),<br> localized MSK (single limb/joint, low back or chest pain), or diffuse MSK<br> (widespread MSK pain)<br><br> - If on medications, they need to be on stable doses of prescribed pain and/or<br> psychiatric medications for 4 weeks before the baseline study visit.<br><br>Exclusion Criteria:<br><br> 1. General Criteria<br><br> - Skin conditions (e.g., eczema) or past skin damage on the arms and legs in or<br> near sites of sensory testing<br><br> - Any comorbid rheumatic disease (e.g., arthritis, lupus), neurological (e.g.,<br> epilepsy, traumatic brain injury) or medical condition (e.g., cancer, diabetes)<br><br> 2. Control Specific Criteria<br><br> - Taking medications that can alter pain sensitivity (e.g., NSAIDs, opioids,<br> stimulants, anticonvulsants; psychiatric)<br><br> 3. Patient Specific Criteria<br><br> - Present psychiatric disease as defined by DSM IV (e.g. psychosis, bipolar<br> disorder, major depression, generalized anxiety disorder), alcohol or drug<br> dependence, or documented developmental delays or impairments (e.g., autism,<br> cerebral palsy, ADHD, or mental retardation) that, in the opinion of the<br> investigator, would interfere with adherence to study requirements or safe<br> participation in the study
Not provided
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Conditioned Pain Modulation (CPM) Profile (Pressure);Conditioned Pain Modulation (CPM) Profile (Heat);Offset Analgesia (OA) Profile;Temporal Summation (TS) Profile;Spatial Summation (SS) Profile
- Secondary Outcome Measures
Name Time Method