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Overlapping Pain Trajectory Study

Recruiting
Conditions
Migraine
Musculoskeletal Pain
Chronic Pain
Widespread Chronic Pain
Low Back Pain
Healthy Volunteers
Functional Abdominal Pain Disorders
Registration Number
NCT05752396
Lead Sponsor
Children's Hospital Medical Center, Cincinnati
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Inclusion Criteria:<br><br> 1. General Criteria<br><br> - Access to the internet either by laptop, tablet, or phone (for REDCap Surveys)<br><br> - English-speaking<br><br> - Parent or guardian willing to comply with protocol, complete study assessments,<br> and provide written informed consent<br><br> 2. Control Specific Criteria<br><br> - No history/active chronic pain<br><br> 3. Patient Specific Criteria<br><br> - Patients will need a diagnosis of a chronic pain derived congruent with ICD-11<br> criteria related to headache (migraine, daily headache), abdominal (FAPD),<br> localized MSK (single limb/joint, low back or chest pain), or diffuse MSK<br> (widespread MSK pain)<br><br> - If on medications, they need to be on stable doses of prescribed pain and/or<br> psychiatric medications for 4 weeks before the baseline study visit.<br><br>Exclusion Criteria:<br><br> 1. General Criteria<br><br> - Skin conditions (e.g., eczema) or past skin damage on the arms and legs in or<br> near sites of sensory testing<br><br> - Any comorbid rheumatic disease (e.g., arthritis, lupus), neurological (e.g.,<br> epilepsy, traumatic brain injury) or medical condition (e.g., cancer, diabetes)<br><br> 2. Control Specific Criteria<br><br> - Taking medications that can alter pain sensitivity (e.g., NSAIDs, opioids,<br> stimulants, anticonvulsants; psychiatric)<br><br> 3. Patient Specific Criteria<br><br> - Present psychiatric disease as defined by DSM IV (e.g. psychosis, bipolar<br> disorder, major depression, generalized anxiety disorder), alcohol or drug<br> dependence, or documented developmental delays or impairments (e.g., autism,<br> cerebral palsy, ADHD, or mental retardation) that, in the opinion of the<br> investigator, would interfere with adherence to study requirements or safe<br> participation in the study

Exclusion Criteria

Not provided

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Conditioned Pain Modulation (CPM) Profile (Pressure);Conditioned Pain Modulation (CPM) Profile (Heat);Offset Analgesia (OA) Profile;Temporal Summation (TS) Profile;Spatial Summation (SS) Profile
Secondary Outcome Measures
NameTimeMethod
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