Effect of Vitamin A Supplementation on Iron Metabolic Homeostasis of Preschool Children in Sichuan,China
- Registration Number
- NCT01355263
- Lead Sponsor
- Chengdu Maternal and Children's Health Care Hospital
- Brief Summary
The investigators plan to perform a randomized, mutual-control and double-blinded cohort study to further exploit the vitamin A supplementation on iron metabolic homeostasis (including iron reserve, mobilization and absorption status in the same population) compared with solely iron and vitamin A plus iron.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 450
Inclusion Criteria
- apparent health;
- Hb concentration>60 g/L;
- C-reaction protein (CRP)<10 mg/L;
- parental or guardian approval of participation in all aspects of the study; and
- parental/guardian agreement to avoid the additional use of vitamin and mineral supplements during the investigation.
Exclusion Criteria
- does not match the inclusion criteria
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description iron tablet, vitamin a capsule iron and vitamin a children in Group I received a 200,000 IU vitamin A capsule just one time initially; Group II received ferrous sulfate (element Fe 1-2 mg/kg•day) once a day for 6 months;.
- Primary Outcome Measures
Name Time Method hemoglobin six months
- Secondary Outcome Measures
Name Time Method