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Comparison of dexmedetomidine mist inhalation to magnesium sulfate in terms of how blood pressure and hear rate responds when a doctor inserts a tube into windpipe and how often the patient gets sore throat after surgery

Phase 1
Registration Number
CTRI/2023/12/060483
Lead Sponsor
Dr Fateh Pal Singh Gill
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.ASA grade I or II fit patients.

2. Patients aged between 18 and 60 years of age.

3. Patients undergoing surgeries under general anaesthesia.

4. Haemodynamically stable patients with all routine investigations within normal limits and without any comorbidities.

5.Written informed consent from the concerned patient.

Exclusion Criteria

1.Patients who are not willing to participate in the study.

2.Patients with ASA grade III and above physical status.

3.Patients who are aged less than 18 and more than 60 years of age.

4. Patients who are posted for emergency procedures.

5. Patients with known allergy to the study drugs.

6. Patients with difficult intubation.

7. Patients who are obese.

8. Patients who have psychiatric, neurological, neuromuscular or cardiovascular disease or impairment of hepatic or renal function.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To observe the attenuation of pressor responses to laryngoscopy and endotracheal intubation with preoperative nebulization with dexmedetomidine and incidence of post operative sore throatTimepoint: Pre intubation, scopy 0 minutes, every 1 minute upto 10 minutes post intubation, after extubation
Secondary Outcome Measures
NameTimeMethod
To observe the attenuation of pressor responses to laryngoscopy and endotracheal intubation with preoperative nebulization with dexmedetomidine and incidence of post operative sore throatTimepoint: Pre intubation, scopy 0 minutes, every 1 minute upto 10 minutes post intubation, after extubation
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