Effect of Traditional Chinese Medicine (TCM) on Embryo Implantation in In-vitro Fertilization (IVF) Patients
试验速览
- 阶段
- 1 期
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- pregnancy rate
研究概览
简要总结
To investigate the impact of traditional Chinese medicines (TCM) on embryonic implantation in the patients who have underwent in vitro fertilization and embryo transfer, the investigators compare the pregnancy rate in traditional Chinese medicine group and control group. The hypothesis is that pregnancy rate in traditional Chinese medicine group is higher than the control group.
详细描述
To demonstrate the impact of traditional Chinese medicine (TCM) on embryo implantation, the investigators perform a prospective randomized study on patients who have underwent in vitro fertilization and embryo transfer (IVF-ET) in the Reproductive Medical Center of the Remin Hospital Wuhan University in the next six months. These patients were randomly divided into two groups, one group was given traditional Chinese medicine, that is, ten days oral administration of Zhuyun recipe from the day after HCG injection. The second group without any treatment, and then the pregnancy rate were observed. Frozen embryo transfer for patients do the same treatment, measured indices were also the same in both groups. Our hypothesis is that Zhuyun recipe is beneficial for embryo implantation in IVF-ET patients, it can be found that pregnancy rate in traditional Chinese medicine group is higher than the control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •aged 18-35 years old
- •undergo IVF/ICSI-ET treatment
- •undergo fresh/ frozen embryos transplantation
排除标准
- •the numbers of embryos transplantation were more than one
- •serum estradiol level > 5000 pg/ml and progesterone level >
- •54 nmol/L on the day of HCG administration
研究组 & 干预措施
traditional Chinese medicine
The pregnancy rate in traditional Chinese medicine group is higher than the control group
干预措施: Traditional Chinese medicine(Zhuyun Recipe) (Drug)
结局指标
主要结局
pregnancy rate
时间窗: Six months
12 days after embryo transplantation, the investigators measured blood hCG level in the patients and its level \> 10IU/L as a biochemical pregnancy, 4 weeks after transplantation, gestational sac and the beating heart were found as clinical pregnancy.
次要结局
未报告次要终点