The effects of protein whey, lipoic acid and protein whey in combination with lipoic acid among acute ischemic stroke patients.
Phase 2
- Conditions
- Ischemic stroke.Cerebral infarction, unspecified
- Registration Number
- IRCT2016061428450N1
- Lead Sponsor
- Vice chancellaor of research and technology , Tabriz university of medical science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
age more than 40 yars old; hospitalized with definite diagnosis of acute ischemic stroke; NIHSS<=20; start of tube feeding in 48 hours after admission.
Exclusion criteria: vegetative ischemic stroke; TPA injected patients; history of chronic diseases (renal failure needing dialysis at admission time); hepatic cirrhosis and liver diseases; chronic respiratory disease; heart failure; history of cancer; epilepsy and GI bleeding; uncontrolled diabetes; history of myocardial infarction in the past 3 months; enteral feeding less than 10 days; alcohol and opioid consumption.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum albumin. Timepoint: base line and 3 weeks later. Method of measurement: Laboratory test, spectophotometric.;Total antioxidant capacity. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Laboratory test, ELIZA.;C reactive protein. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Laboratory test, ELIZA.;?Tnf-a. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Laboratory test, ELIZA.;IL-6. Timepoint: before intervention and 3 weeks after intervention. Method of measurement: Laboratory test, ELIZA.
- Secondary Outcome Measures
Name Time Method IHSS. Timepoint: before intervention, 3 weeks after intervention. Method of measurement: observation with physical examination.;MRS. Timepoint: before intervention, 3 weeks after intervention and 3 months after intervention. Method of measurement: observation with physical examination.;Quality of life. Timepoint: 3 weeks after intervention. Method of measurement: SF-36 Questionnaire.