Investigation of the Effects of Muscle Fatigue in Healthy Young Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- Change in Joint Position Sense (JPS)
研究概览
简要总结
This study aims to investigate the acute effects of fatigue in the tibialis anterior and gastrocnemius muscles on joint position sense, balance, pain threshold, and muscle elasticity in healthy young adults. Muscle fatigue is known to directly affect physical performance and motor function; therefore, understanding its influence on neuromuscular parameters such as proprioception, postural control, and tissue properties is of great importance. By examining how these specific muscle groups respond to fatigue, the study seeks to clarify the role of fatigue in altering joint position sense, balance performance, pain perception, and muscle mechanical properties. The findings of this research are expected to provide new insights that may contribute to the development of more effective strategies in physical therapy and rehabilitation practices.
详细描述
Study Aim and Rationale This study aims to investigate the acute effects of fatigue in the tibialis anterior and gastrocnemius muscles on joint position sense, dynamic balance, muscle elasticity, and pain threshold in healthy young adults. Muscle fatigue is known to directly impact motor function and physical performance; therefore, understanding its influence on neuromuscular parameters such as proprioception, postural control, and biomechanical properties is crucial for developing effective clinical strategies. By evaluating how these specific muscle groups respond to fatigue, the study seeks to generate evidence that can guide physiotherapy and rehabilitation practices.
Methodology A total of 35 healthy adults aged 18-24 who meet the inclusion criteria will participate. All procedures will be conducted at the Physiotherapy and Rehabilitation Laboratory of Istanbul Beykent University. Dominant lower limbs, determined by the foot used in a spontaneous ball-kicking task, will be used for testing. Participants will first undergo a tibialis anterior fatigue protocol, followed one week later by a gastrocnemius fatigue protocol. Each participant will be assessed at four time points: before the fatigue protocol, immediately after, 24 hours later, and 48 hours later.
Participants will be instructed to refrain from high-intensity exercise, stretching, massage, hot/cold applications, and medications for 48 hours prior to testing. These instructions will be provided both verbally and in writing.
Fatigue will be induced through repeated isometric contractions (30 seconds contraction, 15 seconds rest). For tibialis anterior, participants will lie supine and perform dorsiflexion against resistance at a fixed 100° ankle angle using a customized apparatus. For gastrocnemius, participants will lie prone with feet hanging off the table and perform plantarflexion against a wall. Fatigue threshold will be defined as a score ≥7 on the Modified Borg Scale.
Assessments will include:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 24 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aged between 18 and 24 years
- •Body Mass Index (BMI) between 18.5 and 24.9
- •Low to moderate physical activity level
- •No history of neurological or orthopedic disorders
- •Full range of motion in the ankle joint
- •Voluntary participation and informed consent provided
排除标准
- •Does not meet the inclusion criteria
- •History of trauma or surgery in the lower extremities
- •Regular participation in exercise or being a professional athlete
结局指标
主要结局
Change in Joint Position Sense (JPS)
时间窗: Baseline, immediately post-fatigue, 24 hours post-fatigue, 48 hours post-fatigue
Absolute error (in degrees) in ankle joint position sense measured using the active angle reproduction method with the DrGoniometer app. bsolute error (in degrees) in ankle joint position sense measured using the active angle reproduction method with the DrGoniometer app. bsolute error (in degrees) in ankle joint position sense measured using the active angle reproduction method with the DrGoniometer app.
Change in Dynamic Balance Performance
时间窗: Baseline, immediately post-fatigue, 24 hours post-fatigue, 48 hours post-fatigue
Normalized reach distance and composite score from the Modified Star Excursion Balance Test (SEBT) in anterior, posteromedial, and posterolateral directions.
Change in Muscle Elasticity
时间窗: Baseline, immediately post-fatigue, 24 hours post-fatigue, 48 hours post-fatigue
Normalized reach distance and composite score from the Modified Star Excursion Balance Test (SEBT) in anterior, posteromedial, and posterolateral directions.
次要结局
- Force Plate Fatigue Metrics(Baseline and immediately post-fatigue)
研究者
Yasemin Şahbaz
Assistant Profesor
University of Beykent