Effect of lowering the transition metals and ammonium concentration in human culture media on the quality of the human embryos.
- Conditions
- In vitro fertilisation, human embryo, embryo culture, ammonium, transition metals
- Registration Number
- NL-OMON29264
- Lead Sponsor
- GIFT, ZOL, Genk, Belgium Private infertility center in a university-affiliated teaching hospital and Newcastle Fertility Centre at LIFE, Newcastle, UK, University affiliated Center.M. Nijs, GIFT, Genk and Herbert M, LIFE, Newcastle.
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Patients entering the IVF/ICSI program.
Exclusion Criteria
1. ICSI cases for preimplantation genetic diagnosis;
2. ICSI cases with testicular spermatozoa.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Embryo quality (quality and cell number in embryo) and clinical pregnancy rate.
- Secondary Outcome Measures
Name Time Method 1. Metabolomic profiling of embryo culture medium; <br /><br>2. delivery rate; <br /><br>3. health of baby.