Prevalence of Lyme neuroborreliosis among patients with painful radiculopathy visiting a teaching hospital in a Lyme endemic regio

Conditions: 10007951
Lyme disease
Lyme neuroborreliosis
10004018

Registration Number: NL-OMON51614

Lead Sponsor: Gelre Ziekenhuizen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 500

Inclusion Criteria

- All patients visiting the neurology outpatient clinic of Gelre hospitals who
undergo an MRI scan for the indication of painful radiculopathy
- 18 years or older
- Given informed consent for participation in the study

Exclusion Criteria

- Patients who undergo an MRI scan for other reasons than radiculopathy
- Patients who have radiculopathy as a residual symptom after being adequately
treated for Lyme neuroborreliosis
- Patients with a known other explanation for radiculopathy at time of
referral, for example leptomeningeal metastasis or varicella zoster infection

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameters are the result of Borrelia serology<br /><br>(positive/negative) and the result of the MRI scan (yes/no nerve root<br /><br>compression). Patients with positive Borrelia serology and no nerve root<br /><br>compression will be offered a lumbar puncture to test for Lyme<br /><br>neuroborreliosis.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-Differences in patient characteristics and additional symptoms of patients<br /><br>with radiculopathy caused by Lyme neuroborreliosis versus patients with<br /><br>radiculopathy due to nerve root compression.</p><br>