An Online Physical Activity Coaching Intervention for People With PD in Qatar

Not Applicable

Not yet recruiting

• Conditions: Parkinson Disease

• Registration Number: NCT06962930
• Lead Sponsor: Qatar University

Brief Summary

Regular exercise can improve function and quality of life as well as have other positive behavioral and health-related benefits in people Parkinson's disease (PD). Despite the benefits, insufficient exercise is common among PD individuals, often due to common barriers, emphasizing the importance of empowering individuals with adequate knowledge and self-management skills.

This project aims to develop "Engage-Qatar PD," an online physical activity self-management program for people with PD in Qatar. Engage-Qatar PD will be grounded in a previously developed coaching intervention used in people with Huntington's disease (Engage HD) and people with PD. The main focus of this project will be the development work to adapt this intervention for online delivery for people with PD and within the Qatari context.

This development stage will entail participatory design, in which users will be actively involved as co-designers to ensure fully the required cultural adaptations. Following this development phase, a pilot randomized controlled trial will be conducted to assess the feasibility, acceptability, and potential benefits of the developed intervention.

The innovative approach proposed for this project would have wide-reaching impact, advancing the development of new therapeutic options. It will deliver a realistic, culturally adapted therapeutic option for people with PD in Qatar that has the potential to be implemented in a variety of healthcare settings and other countries in the region. Importantly, future work could replicate this program in a larger cohort of individuals with other neurodegenerative diseases and extend this work to other countries in the region.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-04
• Study First Submitted: 2025-04-30
• Study First Submitted QC: 2025-04-30
• Last Update Submitted: 2025-04-30
• Study First Posted: 2025-05-08
• Last Update Posted: 2025-05-08
• Study Start: 2025-05-10
• Primary Completion: 2026-05-10
• Study Completion: 2026-09-10

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Age above 18 years.
2. Successful completion of Physical Activity Readiness Questionnaire (PAR-Q), or medical clearance from a neurologist.
3. Ambulatory for indoor and outdoor mobility with or without an assistive device but without physical assistance.
4. A neurologist-confirmed diagnosis of PD.
5. Ability to follow study-related commands.

Exclusion Criteria

1. Musculoskeletal injury or a medical condition that would prevent safe participation in an exercise program including failure to pass the PAR-Q test.
2. The presence of any other neurological conditions.
3. Acute illness or injury that prevents participation in the intervention.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Objective Physical activity	7 days	7 day physical activity (i.e., step counts and moderate/vigorous activity minutes) using a waist-worn activity monitor (Actigraph)

Secondary Outcome Measures

Name	Time	Method
The Short Self-Efficacy for Exercise Scale (SSEE)	5 minutes	is a self-report questionnaire composed of nine items for the assessment of self-efficacy for exercise
International Physical Activity Questionnaire (IPAQ) short form	5 minutes	This measure will ask about the time spent being physically active in the last 7 days. The purpose of the questionnaires is to provide common instruments that can be used to obtain internationally comparable data on health-related physical activity.
The Physical Activity Scale for Individuals with Physical Disabilities (PASIPD)	less than 5 minutes	Modified disability version of the 10 item Physical Activity Scale for the Elderly (PASE), Captures information about leisure, household, and work-related physical activity over the preceding 7 days, Developed targeting individuals with visual/auditory and locomotor/SCI disabilities.
Six-Minute Walk Test (6MWT)	10 minutes	The 6-Minute Walk test is a measure of endurance. The Subjects will be asked to walk around the perimeter of a set circuit for a total of 6 minutes.
8-item Parkinson's Disease Questionnaire (PDQ-8)	5-10 minutes	The 8-item version of the Parkinson's Disease Questionnaire (PDQ-8) is a shortened version of the 39-item Parkinson's Disease Questionnaire (PDQ-39). It was developed to reduce the respondent burden and increase convenience for use among persons with Parkinson's Disease in clinical settings. PDQ-39 comprises 39 questions from 8 dimensions which include mobility, activities of daily of living, emotional well-being, stigma, social support, cognition, communication, and bodily discomfort.PDQ-8 was constructed by taking one question from each domain of PDQ-39
MDS-UPDRS-II Motor Experiences of Daily Living	10 minutes	The unified Parkinson's disease rating scale (UPDRS) is used to follow the longitudinal course of Parkinson's disease. The UPD rating scale is the most commonly used scale in the clinical study of Parkinson's disease. . It is consisting of 4 parts one of them is MDS-UPDRS-II Motor Experiences of Daily Living it's about motor aspects of experiences of daily living (M-EDL).
MDS-UPDRS-III Motor Examination	15 minutes	The unified Parkinson's disease rating scale (UPDRS) is used to follow the longitudinal course of Parkinson's disease. The UPD rating scale is the most commonly used scale in the clinical study of Parkinson's disease. It is consists of 4 parts one of them is MDS-UPDRS-III Motor Examination its assesses the motor signs of PD
Levodopa Equivalent Daily Doses (LEDD)	5 minutes	The Levodopa Equivalent Daily Dose (LEDD) is a useful calculation for comparing the doses of different Parkinson's disease medications to their equivalent amount of Levodopa. This helps clinicians to evaluate the overall dopaminergic load a patient is receiving. Various Parkinson's medications, such as Levodopa, Dopamine Agonists, and MAO-B inhibitors, can be converted into an equivalent dose of Levodopa using standard conversion factors.
Mini Balance Evaluation Systems Test (Mini-BEST)	10-15 minutes	balance assessment tool is a shortened version of the Balance Evaluation Systems Test (BESTest) consists of 14 items, including 4 of the 6 sections (anticipatory postural adjustments, reactive postural control, sensory orientation, and dynamic gait) from the BESTest. It aims to target and identify 6 different balance control systems so that specific rehabilitation approaches can be designed for different balance deficits. The BESTest was shortened based on factor analysis to include dynamic balance only and to improve clinical utilization.
Five Times Sit to Stand Test (5TSTS)	Less than 5 minutes Depends on the number of trials	The Five Times Sit to Stand Test measures one aspect of transfer skill. The test provides a method to quantify functional lower extremity strength and identify movement strategies a patient uses to complete transitional movements.
the Montréal Cognitive Assessment Scale (MOCA)	10 minutes	(MoCA) was designed as a rapid screening instrument for mild cognitive dysfunction. It assesses different cognitive domains: attention and concentration, executive functions, memory, language, vasoconstrictional skills, conceptual thinking, calculations, and orientation. The MoCA may be administered by anyone who understands and follows the instructions
the Symbol Digit Modalities Test	less than 5 minutes	a commonly used test to assess psychomotor speed, which measures processing speed as well as motor speed. requires an individual to substitute digits for abstract symbols using a reference key. Performance is also affected by attention, visual scanning and tracking, and working memory .The SDMT has excellent psychometric properties, with high reliability and validity .
the Stroop Color-Word Interference	5 minutes	The Stroop Test is a measure of working memory and attention. When the colours and words a conflicting, the brain must work hard to filter out competing signals. Reading is such an automatic task that the brain needs to actively inhibit it and direct its attention instead to saying the colour of the letters. The resulting delay is called the Stroop Effect. When the colours and words match, or when the words are neutral, there is no conflicting information for the brain to have to filter out.
Pittsburgh sleep quality index (PSQI)	5-10 minutes	is a self-report questionnaire that assesses sleep quality over a 1-month time interval. The measure consists of 19 individual items, creating 7 components that produce one global score It is a valuable tool for assessing sleep quality as it captures multiple dimensions of sleep, including both subjective experiences and objective parameters. It allows researchers and healthcare providers alike to obtain a comprehensive understanding of an individual's sleep patterns and disturbances.
10 Meter Walk Test (10MWT)	5 minutes	The 10 Meter Walking Test (10 MWT) assesses short duration walking speed (m/s). It has been used various patient populations including stroke, Parkinson's disease and general neurologic movement disorders.; The 10 Meter Walking Test (10 MWT) is clinician-administered, and measures the time required to walk 10 meters. The test is performed using a "flying start": the patient walks 14m, and the time is measured for the intermediate 10 meters.
Barriers to Being Active Quiz (BBAQ)	5-10 minutes	is a structured questionnaire that measures the barriers to being active consists of 21 questions.
Barriers Subscale of the Physical Fitness	5-10 minutes	It a 21-item measure assessing the following barriers to physical activity: 1) lack of time, 2) social influence, 3) lack of energy, 4) lack of willpower, 5) fear of injury, 6) lack of skill, and 7) lack of resources. Each domain contains 3 items, with a total score range of 0 to 63. Respondents rate the degree of activity interference on a 4-point scale, ranging from 0 = "very unlikely" to 3 = "very likely."
The Modified Fatigue Impact Scale	5-10 minutes	self-report questionnaire provides an assessment of the effects of fatigue in terms of physical, cognitive, and psychosocial functioning and it consists of 21 items.
Barriers to Health Promoting Activities for Disabled Persons Scale (BHADP)	5-10 min	an 18-item, 4-point scale to measure individual barriers to taking care of health. The original scale had 16 items; two additional barrier items, these items address the weather and lack of help from health care professionals. Respondents are asked to indicate how often listed barriers keep them from taking care of their health. Items include intrapersonal, interpersonal, and environmental barriers. Examples of barriers include being too tired, having other responsibilities, and lack of transportation.
the Hospital Anxiety-Depression scale (HADS)	2-5 minutes	is a 14-item scale, with seven items relating to anxiety and seven relating to depression.

Trial Locations

Locations (1)

Qatar University; 🇶🇦 Doha, Qatar