Monitoring of Intraoperative Blood Loss: Benefit of Continuous Noninvasive Haemoglobin Monitoring?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- HbAUC
研究概览
简要总结
Certain types of surgery are associated with occult blood loss, which is hard to detect intraoperatively by intermittent conventional, invasive Hb concentration measurements using the clinical standard of Hb monitoring by satellite laboratory analysis (Hbsatlab). The investigators want to see whether continuous non-invasive transcutaneous Hb measurement using a finger sensor (SpHb), (a) reduces the total time (area under the curve, AUC) a patient's Hb is below a predetermined transfusion threshold (HbAUC) for administration of red blood cell concentrate (RBC), and (b) prevents a decrease in total oxygen delivery (DO2) possibly associated with transfusion below a critical haemoglobin concentration. Furthermore, the investigators want to study if SpHb monitoring changes the timing of RBC administration and reduces the need for intra- and post-operative RBC transfusion.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients at the age of 18 years or older, planned for elective surgery at-risk for undetected blood loss.
- •American Society of Anesthesiologists (ASA) classification I, II, III, IV
排除标准
- •Patient refusal
- •Emergency surgery
结局指标
主要结局
HbAUC
时间窗: during operation
the total time a patient's Hb is below a predetermined transfusion threshold (HbAUC) for administration of red blood cell concentrate
次要结局
- blood transfusions(intra- and post operative up to 48h)
研究者
Prof.dr.T.W.L.Scheeren
Prof.dr.
University Medical Center Groningen
