Assessment of the efficacy of topical gel containing insulin and silver nanoparticles in the treatment of second-degree burn wounds
- Conditions
- Burn patients.Burn and corrosion of head, face, and neck
- Registration Number
- IRCT20210918052511N3
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 56
Patients between the ages of 2 and 60 are eligible to participate.
Patients with second-degree burns diagnosed by the relevant physician
Patients with burns that are less than or equal to 20%
Patient with second-degree burns in upper and lower limbs and anterior trunk
The wound is examined by a plastic and burn surgeon for necrosis and the depth of the burn. If the burned area is not a candidate for early surgery and can be healed without surgery and with minimal complications, the patient will be eligible to the study
Delayed visit and the presence of obvious wound infection at the first visit by an infectious disease specialist
Patients who are receiving chemotherapy
Patients taking corticosteroids or cytotoxic medicines
Pregnancy
Cancer, cytotoxic drugs, immunosuppressants, and the presence of chronic diseases other than diabetes that affect wound healing, such as severe vascular disease, lupus, rheumatoid arthritis, and renal failure
Smoking
The presence of an underlying disease leads to a defective immune system
Diabetic patients
Taking drugs that lead to a defective immune system.
Burns in the back of the trunk, face, head and perineum
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of complete wound healing. Timepoint: Every 48 hours. Method of measurement: Based on the clinical observations of an infectious disease specialist and plastic and burn surgeon.
- Secondary Outcome Measures
Name Time Method Wound condition (presence or absence of granulation tissue, bleeding, pain, infection, and other wound complications or healing factors). Timepoint: Every 48 hours for 2 weeks. Method of measurement: Based on the scores of the variables and presence or absence (yes / no) and based on clinical observations of an infectious disease specialist and subspecialty of plastic surgery and burns.