topical curcumin for treatment of chronic hand eczema
Phase 1
Recruiting
- Conditions
- Chronic Hand Eczema.Other atopic dermatitisL20.8
- Registration Number
- IRCT20240425061563N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
patients above ?? years of age
with chronic hand eczema
who have not received topical or oral treatments for this condition in the past two weeks
consent to participate in the study
Exclusion Criteria
patients younger than ?? years old
pregnancy
breastfeeding
having underlying disease in need of systemic corticosteroids such as adrenal insufficiency and rheumatologic disease
using topical or oral immunomodulators
chronic kidney disease
hepatic insufficiency
the need for more potent corticosteroids (such as clobetasol)
unwillingness to participate in the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of chronic hand eczema. Timepoint: 8 weeks after treatment initiation. Method of measurement: Hand Eczema Severity Index (HECSI).
- Secondary Outcome Measures
Name Time Method Adverse effects of topical curcumin. Timepoint: 8 weeks from initiation of therapy. Method of measurement: interview and physical examination.;Quality of lfe. Timepoint: 8 weeks from initiation of therapy. Method of measurement: Dermatologic Life Quality Index (DLQI).